Yale gave No. 9 Clemson all it could handle for the second straight day.
On Tuesday, Yale led in the seventh. The Bulldogs today scored the first five runs and led 8-6 in the eighth before another heartbreaking, 10-8 loss to the Tigers.
Tim DeGraw, the reigning Ivy League Player of the Week, doubled home Herrera to put Yale up 8-6.
Clemson (14-3) scored four in the eighth to take the lead. Tyler Sapsford (0-1) pitched a scoreless seventh for Yale and took the loss after allowing three earned in the eighth.
Sapsford gave up a one-out, run scoring single. Dey relieved Sapsford, allowed a walk, a sac fly and a two-run double to Chris Williams, who was thrown out a third after the runners had scored.
"Really proud of my guys," Yale head coach John Stuper said. "They gave the number nine team in the country all they could handle for two days. We were seven outs away with a two-run lead Tuesday and six outs away with another two-run lead today. All this with three starters out. I think these two games will serve us well. We just have to figure out how to finish games, and I believe we will. Clemson is a very good team. They had to battle too, and clearly they did."
Yale did more damage with the bases loaded without recording a hit. Tom Ruddy walked in a run and Herrera reached on a catcher's interference to force home another.
Dai Dai Otaka was hit by a pitch to push home a run, and DeGraw worked out a walk to make it 5-0.
The Bulldogs return to action on Friday to begin a four-game series against Wofford of the Southern Conference. Eric Brodkowitz (0-0, 4.38 ERA) will make his third start of the season for Yale against lefty Adam Scott (2-2, 5.82).